SERINC3 Antibody (C-term) [APR31485G]

SERINC3 Antibody (C-term) [APR31485G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SERINC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-400 amino acids from the C-terminal region of human SERINC3.

Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:Q86VE9}; Multi-pass membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9QZI9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9QZI9}

Molecular Weight: 52580

Clone: Polyclonal

Gene Name: SERINC3

Gene ID: 10955

Function: Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734) .

Summary: Tissue Location: Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Serine incorporator 3, Tumor differentially expressed protein 1, SERINC3, DIFF33, TDE1