SERPINB5 Polyclonal Antibody | E-AB-10447

SERPINB5 Polyclonal Antibody | E-AB-10447 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Maspin, Ovalbumin, Peptidase inhibitor 5, PI-5, PI5, protease inhibitor 5 (maspin), Protease inhibitor 5, Serine (or cysteine) peptidase inhibitor, clade B, member 5, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5, Serpin B5, serpin family B member 5, Serpin peptidase inhibitor, Serpin peptidase inhibitor, clade B (ovalbumin), member 5, Serpinb5, SPB5, Spi5, Spi7

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer

Background: Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human SERPINB5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 42 kDa

Molecular Weight(Observed): N/A