SERPIND1 Antibody | 19-896

SERPIND1 Antibody | 19-896 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2) .

Research Area: Other

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: A-431

Positive Control 3: HepG2

Positive Control 4: 293T

Positive Control 5: Mouse liver

Positive Control 6: Mouse pancreas

Molecular Weight: Observed: 57-69kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH1heparin cofactor 2, leuserpin 2, protease inhibitor leuserpin-2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor) , member 1, serpin D1, serpin peptidase inhibitor, clade D (heparin cofactor) , member 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.