SESN3 Polyclonal Antibody | E-AB-63213

SESN3 Polyclonal Antibody | E-AB-63213 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: SESN3, SEST3, sestrin-3

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism

Background: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human SESN3 (NP_653266.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 36 kDa/41 kDa/57 kDa

Molecular Weight(Observed): 50 kDa