SETD2 Polyclonal Antibody | E-AB-10851

SETD2 Polyclonal Antibody | E-AB-10851 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: EC 2.1.1.43, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HBP231, HIF 1, HIF-1, HIF1, HIP-1, Histone lysine N methyltransferase SETD2, Histone-lysine N-methyltransferase SETD2, hSET2, HSPC069, Huntingtin interacting protein 1, Huntingtin interacting protein, Huntingtin interacting protein B, Huntingtin interacting protein HYPB, Huntingtin yeast partner B, Huntingtin-binding protein, 231-KD, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPB, KIAA1732, KMT3A, Lysine N methyltransferase 3A, Lysine N-methyltransferase 3A, p231HBP, SET domain containing 2, SET domain-containing protein 2, SET2, SETD2, SETD2

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human SETD2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A