BW
SETD7 polyclonal Antibody | BS71399
- SKU:
- BW-BS71399
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- Usually ships in 5 working days
Description
SETD7 polyclonal Antibody | BS71399 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SETD7 polyclonal Antibody detects endogenous levels of SETD7 protein.
Molecular Weight: ~ 41 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: SET7/9; KIAA1717, KMT7, SET7, SET9
Immunogen: Recombinant protein of human SETD7.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: DNA Methylation,