SETDB1 Antibody | 22-030

SETDB1 Antibody | 22-030 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-397 of human SETDB1 (NP_001230420.1) .

Research Area: Other

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: MCF7

Positive Control 3: DU145

Positive Control 4: HL-60

Positive Control 5: Jurkat

Positive Control 6: 293T

Molecular Weight: Observed: 210kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: SETDB1, H3-K9-HMTase4, ESET, KMT1E, H3-K9-HMTase 4, KG1T, SET domain, bifurcated 1, SET domain bifurcated 1, KIAA0067, Lysine N-methyltransferase 1E

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.