SETMAR Polyclonal Antibody | E-AB-18994

SETMAR Polyclonal Antibody | E-AB-18994 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Histone lysine N methyltransferase, Histone lysine N methyltransferase SETMAR, Hsmar 1, Hsmar1, Mariner transposase Hsmar1, Metnase, SET domain and mariner transposase fusion, SET domain and mariner transposase fusion gene, SET domain and mariner transposase fusion gene containing protein, SET domain and mariner transposase fusion gene-containing protein, Setmar, SETMR

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Concentration: 1.08 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human SETMAR

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A