SFRP1 polyclonal Antibody | BS91233

SFRP1 polyclonal Antibody | BS91233 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB:1:500-1:2,000

Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity) . Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity) . In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity) . Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SFRP1 polyclonal Antibody detects endogenous levels of SFRP1 protein.

Molecular Weight: 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FRP-1, sFRP-1, SARP-2, SFRP1, Frizzled related protein 1, FRP 1, FRP, FRP-1, FRP1, FrzA, SARP 2, SARP-2, SARP2, Secreted apoptosis related protein 2, Secreted apoptosis-related protein 2, Secreted frizzled related protein 1, Secreted frizzled related protein, Secreted frizzled-related protein 1, SFRP 1, sFRP-1, SFRP1, SFRP1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: