SGSM3 Antibody | 7037

SGSM3 Antibody | 7037 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Rat: (82%) , Mouse: (82%) , Bovine: (79%)

Immunogen: SGSM3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human SGSM3.
The immunogen is located within amino acids 30 - 80 of SGSM3.

Research Area: Signal Transduction

Tested Application: E, WB, IF

Application: SGSM3 antibody can be used for detection of SGSM3 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: Multiple isoforms of SGSM3 are known to exist. SGSM3 antibody is predicted to not cross react with other SGSM family proteins.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: Cat. No. 17-010 - HEK293 Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 82 kDa

Validation: N/A

Isoform: N/A

Purification: SGSM3 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SGSM3 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SGSM3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SGSM3 Antibody: MAP, RUSC3, RUTBC3, RABGAP5, RabGAP-5, MAP, RABGAPLP, Small G protein signaling modulator 3, Merlin-associated protein, RabGAPLP

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SGSM3 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation.  A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. Little is known of the exact function of SGSM3.