SH3BGR Antibody | 58-788

SH3BGR Antibody | 58-788 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: This SH3BGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the Central region of human SH3BGR.

Research Area: Signal Transduction

Tested Application: WB

Application: For WB starting dilution is: 1:1000

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 26 kDa

Validation: N/A

Isoform: N/A

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality: Polyclonal

Clone: N/A

Isotype: Rabbit Ig

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration: batch dependent

Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SH3 domain-binding glutamic acid-rich protein, SH3BGR protein, 21-glutamic acid-rich protein, 21-GARP, SH3BGR

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways. SH3 domain binding glutamic acid-rich protein (SH3BGR) , also designated 21-glutamic acid-rich protein (21-GARP) , is a 239-amino acid protein differentially expressed in heart and skeletal muscle. Its proline-rich region contains the consensus sequence for an SH3-binding domain and its acidic C-terminal region contains a glutamic acid-rich domain which may assume a coiled-coil structure. SH3BGR may be part of a multimeric complex, as it contains 2 functional domains involved in protein-protein interactions.