SH3GL2 Antibody (C-term) [APR33203G]

SH3GL2 Antibody (C-term) [APR33203G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This SH3GL2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 245-279 amino acids from the C-terminal region of human SH3GL2.

Cellular Localisation: Cytoplasm {ECO:0000250|UniProtKB:O35179}. Membrane {ECO:0000250|UniProtKB:O35179}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35179}. Early endosome {ECO:0000250|UniProtKB:Q62420}. Cell junction, synapse, presynapse {ECO:0000250|UniProtKB:O35179}

Molecular Weight: 39962

Clone: Polyclonal

Gene Name: SH3GL2

Gene ID: 6456

Function: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.

Summary: Tissue Location: Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A