LBD
SH3PXD2B Antibody (Center) [ApR05034G]
- SKU:
- LBD-ApR05034G
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Description
SH3PXD2B Antibody (Center) [ApR05034G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SH3PXD2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 505-539 amino acids from the Central region of human SH3PXD2B.
Cellular Localisation: Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells.
Molecular Weight: 101579
Clone: Polyclonal
Gene Name: SH3PXD2B
Gene ID: 285590
Function: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity) .
Summary: Tissue Location: Expressed in fibroblasts.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: N/A