552

Sheep Anti-Human Apolipoprotein AII Neat Antiserum | ABMC-S05

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SKU:
552-S05-GEN
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NULL376.00

Description

Sheep Anti-Human Apolipoprotein AII Neat Antiserum |S05

Host Species: Sheep
Antigen: Human Apolipoprotein AII
Specificity

Specifically binds to human apo AII. Dilution for immunoblot and ELISA range: 1,000 to 320,000.
Use:

The antibody can be used for detection of human apo AII in human plasma and lipoproteins, using immunoassays or immunoblots.
Storage: -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing.

 

IMPORTANCE

Apo AII comprises 25% of HDL. It exists in human plasma as a dimer of 2 identical chains of 77 amino acid residues, joined by disulfide. The molecular weight is reported to be 8.7 kDa for a single chain (Brewer et al., 1972).

Studies on mouse reported that apo AII may be proatherogenic (Warden et al., 1993); however, case-control study in the large European Prospective Investigation demonstrated that plasma Apo AII concentrations were strongly inversely correlated with CHD events (Birjmohun et al., 2007).

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