SHMT1 Polyclonal Antibody | E-AB-64205

SHMT1 Polyclonal Antibody | E-AB-64205 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: SHMT1, CSHMT, SHMT

Application: WB, IHC, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signal Transduction

Background: This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human SHMT1 (NP_683718.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 37 kDa/44 kDa/49 kDa/53 kDa

Molecular Weight(Observed): 53 kDa