SIGLEC8 Polyclonal Antibody | E-AB-64057

SIGLEC8 Polyclonal Antibody | E-AB-64057 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology, Signal Transduction

Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein .

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human SIGLEC8 (NP_055257.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 44 kDa/46 kDa/54 kDa

Molecular Weight(Observed): 60 kDa