Description
SIK1 Polyclonal Antibody | E-AB-16864 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: KID2, MSK, myocardial SNF1 like kinase, QIK, Qin-induced kinase, Salt inducible kinase 1, Salt-inducible protein kinase 1, Serine threonine protein kinase SNF1 like kinase 1, Serine threonine protein kinase SNF1LK, Serine/threonine-protein kinase SIK1, Serine/threonine-protein kinase SNF1-like kinase 1, Serine/threonine-protein kinase SNF1LK, SIK-1, SIK1, SIK1, SNF1 like kinase
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell biology, Cardiovascular, Epigenetics and Nuclear Signaling, Signal transduction
Background: SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.
Concentration: 0.8 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human SIK1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 85 kDa
Molecular Weight(Observed): N/A