SIK2 polyclonal Antibody | BS71160

SIK2 polyclonal Antibody | BS71160 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: QIK (Qin-induced kinase) is a serine/threonine-protein kinase that belongs to the AMPK/SNF1 kinase family. Also designated SIK2 (SNF1-like kinase 2), QIK is one of twelve human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK) related to AMPK. QIK is a ubiquitously expressed protein and is rapidly upregulated after a hormone-regulated form of Qin is activated. In vitro kinase tests demonstrate that QIK is capable of autophosphorylation. Elevated levels of QIK transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SIK2 polyclonal Antibody detects endogenous levels of SIK2 protein.

Molecular Weight: ~ 129 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: QIK; SIK-2; SNF1LK2; LOH11CR1I;

Immunogen: Recombinant protein of human SIK2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: