Sin Nombre Virus Glycoprotein 2 Antibody | 7683

Sin Nombre Virus Glycoprotein 2 Antibody | 7683 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Virus

Homology: N/A

Immunogen: Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein.
The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2.

Research Area: Infectious Disease

Tested Application: E

Application: Sin Nombre virus glycoprotein 2 antibody can detect 10ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μg/ml.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Sin Nombre virus glycoprotein 2 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: Sin Nombre Glycoprotein 2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Sin Nombre Virus Glycoprotein 2 Antibody:

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1) . Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc) . While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2) , no such degradation was observed for the G2 glycoprotein.