Sintilimab (PDCD1/PD1/CD279) Antibody, Monoclonal | 10-919

Sintilimab (PDCD1/PD1/CD279) Antibody, Monoclonal | 10-919 | Gentaur UK, US & Europe Distribution

Host: N/A

Reactivity: N/A

Homology: N/A

Immunogen: Homo sapiens / PDCD1/PD1/CD279 [Homo sapiens]

Research Area: Drug Analogues

Tested Application: N/A

Application: N/A

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: >95%

Clonality: Monoclonal

Clone: N/A

Isotype: IgG4-kappa

Conjugate: Unconjugated

Physical State: N/A

Buffer: PBS buffer pH7.5

Concentration: N/A

Storage Condition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.

Alternate Name: IBI-308

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Sintilimab is fully human anti-PD-1 antibody used for tumor immunotherapy. It adopts the IgG4 molecular framework and has its hinge region sequence modified (S228P) . Sindilimum acts as a blocker of programmed death receptor 1 (PD-1) , which can bind to PD-1 molecule on the surface of T cells and release the inhibitory effect of the PD-1 pathway on T cells.