SIP1 (E101) polyclonal Antibody | BS3009

SIP1 (E101) polyclonal Antibody | BS3009 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: SIP1, also known as SMADIP1 and ZFHX1B, can be induced by TGFβ treatment. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. The human SIP1 gene maps to chromosome 2q22. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR) . Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart disease—all symptoms of HSCR.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SIP1 (E101) pAb detects endogenous levels of SIP1 protein.

Molecular Weight: ~ 157 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Zinc finger E-box-binding homeobox 2; Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b; ZEB2; KIAA0569; SIP1; ZFHX1B; ZFX1B; HRIHFB2411

Immunogen: Synthetic peptide, corresponding to amino acids 71-120 of Human SIP1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: