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SIP1 (E101) polyclonal Antibody | BS3009
- SKU:
- BW-BS3009
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- Usually ships in 5 working days
Description
SIP1 (E101) polyclonal Antibody | BS3009 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: SIP1, also known as SMADIP1 and ZFHX1B, can be induced by TGFβ treatment. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. The human SIP1 gene maps to chromosome 2q22. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR) . Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart disease—all symptoms of HSCR.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SIP1 (E101) pAb detects endogenous levels of SIP1 protein.
Molecular Weight: ~ 157 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Zinc finger E-box-binding homeobox 2; Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b; ZEB2; KIAA0569; SIP1; ZFHX1B; ZFX1B; HRIHFB2411
Immunogen: Synthetic peptide, corresponding to amino acids 71-120 of Human SIP1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: