SKQ1 Bromide | B2584

SKQ1 bromide is a cell-permeable mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). SKQ1 prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer’s disease, as well as decreases severity of arthritic lesions in rats. SKQ1 could be a promising candidate for therapy for MS and related neurological disorders.

SKQ1 bromide is a cell-permeable mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). SKQ1 prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer’s disease, as well as decreases severity of arthritic lesions in rats. SKQ1 could be a promising candidate for therapy for MS and related neurological disorders.

B2584 | SKQ1 Bromide DataSheet

Alternate Name/Synonyms: Plastoquinonyl decyltriphenyl phosphonium bromide, (10-(4,5-dimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl)triphenylphosphonium bromide, Visomitin, PDTP

Appearance: Liquid

Formulation: A solution (200 mg/ml) in Ethanol:water (1:1, v/v)

CAS Number: 934826-68-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₆H₄₂BrO₂P

Molecular Weight: 617.61

Cell-Permeable?: True

Purity: ≥98%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent mitochondria-targeted antioxidant

MDL Number:

PubChem CID: 16679091

SMILES: CC1=C(C(=O)C(=CC1=O)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

InChi: InChI=1S/C36H42O2P.BrH/c1-29-30(2)36(38)31(28-35(29)37)20-12-7-5-3-4-6-8-19-27-39(32-21-13-9-14-22-32,33-23-15-10-16-24-33)34-25-17-11-18-26-34;/h9-11,13-18,21-26,28H,3-8,12,19-20,27H2,1-2H3;1H/q+1;/p-1

InChi Key: