SLA2 Antibody (Center) [AMM07831G]

SLA2 Antibody (Center) [AMM07831G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This SLA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 138-169 amino acids from the Central region of human SLA2.

Cellular Localisation: Cytoplasm. [Isoform 2]: Cytoplasm. Note=May be cytoplasmic and is not localized to membranes

Molecular Weight: 28585

Clone: Polyclonal

Gene Name: SLA2

Gene ID: 84174

Function: Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.

Summary: Tissue Location: Predominantly expressed in immune system, with highest levels in peripheral blood leukocytes. Expressed in spleen, thymus and lymph nodes. Expressed in T-cells as well as in monocytes, and at low level in B-cells. Also detected in placenta, prostate, skin, retina and colon

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Src-like-adapter 2, Modulator of antigen receptor signaling, MARS, Src-like adapter protein 2, SLAP-2, SLA2, C20orf156, SLAP2