SLAIN2 Antibody | 5471

SLAIN2 Antibody | 5471 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (100%) , Mouse: (93%)

Immunogen: SLAIN2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human SLAIN2.
The immunogen is located within amino acids 70 - 120 of SLAIN2.

Research Area: Stem Cell

Tested Application: E, IHC-P

Application: SLAIN2 antibody can be used for detection of SLAIN2 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Specificiy: SLAIN2 antibody is predicted not to cross-react with SLAIN1.

Positive Control 1: Cat. No. 11-701 - Human Testis Tissue Slide

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 64 kDa

Validation: N/A

Isoform: N/A

Purification: SLAIN2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLAIN2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLAIN2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SLAIN2 Antibody: KIAA1458, KIAA1458, SLAIN motif-containing protein 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs) , cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.