SLC11A1 Antibody | 29-902

SLC11A1 Antibody | 29-902 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC11A1.

Research Area: Membrane, Cancer

Tested Application: E, WB

Application: SLC11A1 antibody can be used for detection of SLC11A1 by ELISA at 1:1562500. SLC11A1 antibody can be used for detection of SLC11A1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 61 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC11A1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: SLC11A1, LSH, NRAMP, NRAMP1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.