SLC15A1 polyclonal Antibody | BS5847

SLC15A1 polyclonal Antibody | BS5847 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins. PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues. Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential. PEPT1 is 708 amino acid protein that contains 12 putative membrane-spanning domains. PEPT1 is expressed in Caco-2 cells. PEPT1 seems to play important roles in nutritional and pharmacological therapies. The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC15A1 polyclonal Antibody detects endogenous levels of SLC15A1 protein.

Molecular Weight: ~ 78 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Solute carrier family 15 member 1; Intestinal H (+) /peptide cotransporter; Oligopeptide transporter, small intestine isoform; Peptide transporter 1; PEPT1

Immunogen: Synthetic peptide, corresponding to amino acids 269-314 of Human SLC15A1.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A