SLC15A3 Antibody (Center) [APR31042G]

SLC15A3 Antibody (Center) [APR31042G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SLC15A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human SLC15A3.

Cellular Localisation: Lysosome membrane; Multi-pass membrane protein. Endosome membrane {ECO:0000250|UniProtKB:Q8BPX9}; Multi-pass membrane protein

Molecular Weight: 63560

Clone: Polyclonal

Gene Name: SLC15A3 (HGNC:18068)

Gene ID: 51296

Function: Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity) . Also able to transport carnosine (PubMed:31073693) . Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: WB--1:2000

Synonyms: Solute carrier family 15 member 3, Osteoclast transporter, Peptide transporter 3, Peptide/histidine transporter 2, SLC15A3, OCTP, PHT2, PTR3