SLC17A6 Antibody (Center) [APR33631G]

SLC17A6 Antibody (Center) [APR33631G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This SLC17A6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 255-289 amino acids of human SLC17A6.

Cellular Localisation: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q8BLE7}; Multi-pass membrane protein. Cell junction, synapse, synaptosome {ECO:0000250|UniProtKB:Q8BLE7}

Molecular Weight: 64392

Clone: Polyclonal

Gene Name: SLC17A6

Gene ID: 57084

Function: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:11698620) . May also mediate the transport of inorganic phosphate (PubMed:10820226) . Involved in the regulation of retinal hyaloid vessel regression during postnatal development (By similarity) .

Summary: Tissue Location: Predominantly expressed in adult brain (PubMed:10820226) . Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, putamen, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus (PubMed:10820226) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Vesicular glutamate transporter 2, VGluT2, Differentiation-associated BNPI, Differentiation-associated Na (+) -dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6, SLC17A6, DNPI, VGLUT2