SLC1A2 Antibody | 13-320

SLC1A2 Antibody | 13-320 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 495-574 of human SLC1A2 (NP_004162.2) .

Research Area: Neuroscience, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:500 - 1:5000
IHC: 1:100 - 1:200

Specificiy: N/A

Positive Control 1: MCF7

Positive Control 2: HepG2

Positive Control 3: SW480

Positive Control 4: Mouse liver

Positive Control 5: Rat liver

Positive Control 6: N/A

Molecular Weight: Observed: 65kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: EAAT2, EIEE41, GLT-1, HBGT, excitatory amino acid transporter 2, excitotoxic amino acid transporter 2, glutamate/aspartate transporter II, sodium-dependent glutamate/aspartate transporter 2, solute carrier family 1 (glial high affinity glutamate transporter) , member 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.