SLC22A17 Polyclonal Antibody | E-AB-12870

SLC22A17 Polyclonal Antibody | E-AB-12870 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 24p3 receptor, 24p3R, BOCT, BOIT, Brain type organic cation transporter, Brain-type organic cation transporter, hBOIT, Lipocalin-2 receptor, Neutrophil gelatinase associated lipocalin receptor, Neutrophil gelatinase-associated lipocalin receptor, NGAL receptor, NgalR, NGALR2, NGALR3, OTTHUMP00000082690, OTTHUMP00000082691, Potent brain type organic ion transporter, S22AH, Slc22a17, Solute carrier family 22 member 17, Solute carrier family 22 organic cation transporter member 17

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human SLC22A17

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A