LBD
SLC28A1 Antibody (Center) [APR32789G]
- SKU:
- LBD-APR32789G
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Description
SLC28A1 Antibody (Center) [APR32789G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SLC28A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-409 amino acids from the Central region of human SLC28A1.
Cellular Localisation: Cell membrane; Multi-pass membrane protein
Molecular Weight: 71584
Clone: Polyclonal
Gene Name: SLC28A1
Gene ID: 9154
Function: Sodium-dependent and pyrimidine-selective transporter (PubMed:21998139) . Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine) . Transports uridine, cytidine, thymidine, and nucleoside-derived drugs (PubMed:21998139) . Transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2', 3'-dideoxycytidine (ddC) . It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS) . It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.
Summary: Tissue Location: Expressed in kidney.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Sodium/nucleoside cotransporter 1, Concentrative nucleoside transporter 1, CNT 1, hCNT1, Na (+) /nucleoside cotransporter 1, Sodium-coupled nucleoside transporter 1, Solute carrier family 28 member 1, SLC28A1, CNT1