223

SLC29A4 Antibody | 8131

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SKU:
223-8131-GEN
NULL341.00 - NULL647.00

Description

SLC29A4 Antibody | 8131 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Mouse: (94%)

Immunogen: SLC29A4 antibody was raised against an 18 amino acid peptide near the center of human SLC29A4.
The immunogen is located within amino acids 310 - 360 of SLC29A4.

Research Area: Cancer, Neuroscience

Tested Application: E, WB, IHC-P, IF

Application: SLC29A4 antibody can be used for detection of SLC29A4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: SLC29A4 antibody is human specific. SLC29A4 antibody is predicted to not cross-react with other SLC29 proteins.

Positive Control 1: Cat. No. 1220 - SK-N-SH Cell Lysate

Positive Control 2: Cat. No. 10-301 - Human Brain Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 58 kDa
Observed: 58 kDa

Validation: N/A

Isoform: N/A

Purification: SLC29A4 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLC29A4 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLC29A4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Solute carrier family 29 member 4, Equilibrative nucleoside transporter 4, ENT4, PMAT

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLC29A4 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1, 2) . SLC29A4 is a transmembrane protein that catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling (1, 3) . SLC29A4 has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium (3) .

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