SLC38A4 Antibody | 8343

SLC38A4 Antibody | 8343 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: Predicted species reactivity based on immunogen sequence: Rat: (71%)

Immunogen: SLC38A4 antibody was raised against an 18 amino acid peptide from near the center of human SLC38A4.
The immunogen is located within amino acids 270 - 320 of SLC38A4.

Research Area: Stem Cell, Homeostasis

Tested Application: E, WB, IHC-P

Application: SLC38A4 antibody can be used for the detection of SLC38A4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Specificiy: SLC38A4 antibody is human and mouse reactive. SLC38A4 will not cross-react with other members of the SLC38 protein family.

Positive Control 1: Cat. No. 1405 - Mouse Kidney Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 60 kDa
Observed: 60 kDa

Validation: N/A

Isoform: N/A

Purification: SLC38A4 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLC38A4 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLC38A4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Solute carrier family 38 member 4, sodium-coupled neutral amino acid transporter 4, SNAT4, protein associated with ABC transporters, PAAT, ATA3, NAT3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids (1, 2) . The transport of cationic amino acids by SLC38A4 is sodium and pH independent, while the transport of neutral amino acids is sodium and pH dependent (2) . Recent evidence suggests that SLC38A4 functions as a regulator of protein synthesis downstream of the hepatocyte nuclear factor 4a during liver development (3) . It has also been suggested that SLC38A4 has ATPase activity and is critically involved in the maintenance of mitochondrial homeostasis and cell survival (4) .