SLC5A4 Antibody (C-term) [AMM07873G]

SLC5A4 Antibody (C-term) [AMM07873G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SLC5A4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 621-655 amino acids from the C-terminal region of human SLC5A4.

Cellular Localisation: Cell membrane; Multi-pass membrane protein

Molecular Weight: 72456

Clone: Polyclonal

Gene Name: SLC5A4 {ECO:0000303|PubMed:13130073}

Gene ID: 6527

Function: Has electrogenic activity in response to glucose, and may function as a glucose sensor (PubMed:13130073, PubMed:17110502, PubMed:20421923, PubMed:22766068) . Mediates influx of sodium ions into the cell but does not transport sugars (PubMed:13130073, PubMed:22766068) . Also potently activated by imino sugars such as deoxynojirimycin (DNJ) (PubMed:17110502, PubMed:20421923, PubMed:22766068) .

Summary: Tissue Location: Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level) (PubMed:13130073) Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level) (PubMed:13130073) . Detected in kidney (at protein level) (PubMed:22766068) .

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Low affinity sodium-glucose cotransporter, Sodium/glucose cotransporter 3, Na (+) /glucose cotransporter 3, Solute carrier family 5 member 4, SLC5A4, SAAT1, SGLT2