SLC9A3R1 polyclonal Antibody | BS70037

SLC9A3R1 polyclonal Antibody | BS70037 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:1000 - 1:4000

Background: NHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC9A3R1 polyclonal Antibody detects endogenous levels of SLC9A3R1 protein.

Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: EBP50;NHERF;NHERF-1;NHERF1;NPHLOP2;Regulatory cofactor of Na (+) /H (+) exchanger Antibody;Sodium-hydrogen exchanger regulatory factor 1 Antibody;Solute carrier family 9 isoform A3 regulatory factor 1 Antibody;

Immunogen: Recombinant protein of human SLC9A3R1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Apoptosis,Inhibition of Apoptosis,Mitochondrial Control of Apoptosis,Death Receptor Signaling,