SLN13 Antibody (C-term) [APR04290G]

SLN13 Antibody (C-term) [APR04290G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SLN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 632-663 amino acids from the C-terminal region of human SLN13.

Cellular Localisation: Cytoplasm.

Molecular Weight: 102045

Clone: Polyclonal

Gene Name: SLFN13 (HGNC:26481)

Gene ID: 146857

Function: Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550) . Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550) . Does not act on tRNA (Sec) (PubMed:29563550) . Able to restrict HIV-1 virus replication; ability to inhibit HIV-1 replication is dependent on endoribonuclease activity (PubMed:29563550) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Schlafen family member 13, SLFN13