α-SMA Rabbit monoclonal Antibody | BS9908M

α-SMA Rabbit monoclonal Antibody | BS9908M | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat, Zebra fish

Application: WB IHC FC

Application Range: WB: 1:1000-1:5000 IHC: 1:50-1:200 FC: 1:50-1:100

Background: Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of α-SMA and does not cross-react with related proteins.

Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ACTA2; AAT6; ACTSA; MYMY5; Actin, aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; alpha-SMA; a-SMA; aSMA; SMA-alpha;

Immunogen: Recombinant Antibody.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified

Pathway: