Smad1 polyclonal Antibody | BS91250

Smad1 polyclonal Antibody | BS91250 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB ICC/IF

Application Range: WB:1:500-1:1,000 ICC:1:100-1:500

Background: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Smad1 polyclonal Antibody detects endogenous levels of Smad1 protein.

Molecular Weight: 52 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MAD homolog 1, Mothers against DPP homolog 1, SMAD 1, Smad1, hSMAD1, BSP-1, SMAD1, BSP-1, BSP1, HsMAD1, JV4-1, JV41, MAD homolog 1, MAD mothers against decapentaplegic homolog 1, Mad related protein 1, Mad-related protein 1, MADH1, MADR1, Mothers against decapentaplegic homolog 1, Mothers against DPP homolog 1, SMA- AND MAD-RELATED PROTEIN 1, SMAD 1, SMAD family member 1, SMAD mothers against DPP homolog 1, Smad1, SMAD1, TGF beta signaling protein 1, Transforming growth factor-beta-signaling protein 1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: TGFβ Smad signaling,