Description
SMC6 Polyclonal Antibody | BS65989 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,
Application: IHC-P,
Application Range: IHC-P=1:100-500
Background: SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SMC6 Polyclonal Antibody detects endogenous levels of SMC6 protein.
Molecular Weight: 126 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: SMC6L1; SMC 6; SMC6; SMC6 protein; SMC6 structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes 6; Structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes protein 6.
Immunogen: KLH conjugated synthetic peptide derived from human SMC6:155-260/1091
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway: