SMG7 Antibody (C-term) [APR32948G]

SMG7 Antibody (C-term) [APR32948G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SMG7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 896-930 amino acids from the C-terminal region of human SMG7.

Cellular Localisation: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm

Molecular Weight: 127282

Clone: Polyclonal

Gene Name: SMG7

Gene ID: 9887

Function: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:500-1:1000

Synonyms: Protein SMG7, EST1-like protein C, SMG-7 homolog, hSMG-7, SMG7, C1orf16, EST1C, KIAA0250