SMI-16a | B2275

SMI-16a is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC₅₀ = 150 nM and 20 nM against Pim-1 and Pim-2, respectively).

SMI-16a is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC₅₀ = 150 nM and 20 nM against Pim-1 and Pim-2, respectively).

B2275 | SMI-16a DataSheet

Alternate Name/Synonyms: (Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione; Pim1/2 Inhibitor IV

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 587852-28-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₁₃NO₃S

Molecular Weight: 263.31

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases

MDL Number: N/A

PubChem CID: 4349931

SMILES: CCCOC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2

InChi: InChI=1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)

InChi Key: GBWOSXZUTXXXQF-UHFFFAOYSA-N