Smo Agonist, SAG | 1939

Cell-permeable. A Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.

Smo Agonist, SAG is a Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.

1939 | Smo Agonist, SAG DataSheet

Alternate Name/Synonyms: N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane

Appearance: Off-white solid

Formulation: N/A

CAS Number: 912545-86-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₂₈ClN₃OS

Molecular Weight: 490.06

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO (>40 mg/ml)

Handling: Protect from light

Country of Origin: USA

Tag Line: A Smoothened (Smo) agonist

MDL Number: N/A

PubChem CID: N/A

SMILES: N/A

InChi: N/A

InChi Key: N/A