SMTNL1 Antibody (Center) [APR30796G]

SMTNL1 Antibody (Center) [APR30796G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SMTNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human SMTNL1.

Cellular Localisation: Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity) Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity) .

Molecular Weight: 52987

Clone: Polyclonal

Gene Name: SMTNL1

Gene ID: 219537

Function: Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity) .

Summary: Tissue Location: Expressed in striated muscles, specifically in type 2a fibers (at protein level) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:2000

Synonyms: Smoothelin-like protein 1, SMTNL1