SMUG1 polyclonal Antibody | BS5753

SMUG1 polyclonal Antibody | BS5753 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC ICC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200

Background: The base excision repair (BER) pathway removes incorrect bases (uracil) or damaged bases (3-methyladenine) from chromatin. Each BER enzyme system addresses a specific type of base damage. Uracil-DNA glycosylases, UNG2 and SMUG1 (single-strand selective monofunctional uracil DNA glycosylase) remove uracil from both double- and single-stranded DNA in nucleosomes (chromatin core particle) . The uracil-excising enzyme family shares structural and functional conservation with minimal sequence conservation. The human SMUG1 gene maps to chromosome 12q13.13.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SMUG1 polyclonal Antibody detects endogenous levels of SMUG1 protein.

Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Single-strand selective monofunctional uracil DNA glycosylase

Immunogen: Synthetic peptide, corresponding to amino acids 137-182 of Human SMUG1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: