Description
SMUG1 polyclonal Antibody | BS5753 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC ICC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200
Background: The base excision repair (BER) pathway removes incorrect bases (uracil) or damaged bases (3-methyladenine) from chromatin. Each BER enzyme system addresses a specific type of base damage. Uracil-DNA glycosylases, UNG2 and SMUG1 (single-strand selective monofunctional uracil DNA glycosylase) remove uracil from both double- and single-stranded DNA in nucleosomes (chromatin core particle) . The uracil-excising enzyme family shares structural and functional conservation with minimal sequence conservation. The human SMUG1 gene maps to chromosome 12q13.13.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SMUG1 polyclonal Antibody detects endogenous levels of SMUG1 protein.
Molecular Weight: ~ 34 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Single-strand selective monofunctional uracil DNA glycosylase
Immunogen: Synthetic peptide, corresponding to amino acids 137-182 of Human SMUG1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: