SMYD2 monoclonal Antibody | MB0147

SMYD2 monoclonal Antibody | MB0147 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse

Application: WB

Application Range: WB: 1:1000

Background: SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regulation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of SMYD2 and does not cross-react with related proteins

Molecular Weight: Predicted band size:50KDa Observed band size:50KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HSKM-B; Histone methyltransferase SMYD2,EC=2.1.1.43; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2; KMT3C; HSKM-B; ZMYND14

Immunogen: Recombinant full length Human SMYD2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: T cell receptor signaling,