Description
SNCA Antibody | 13-004 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide of human SNCA
Research Area: Apoptosis, Cell Cycle, Neuroscience
Tested Application: WB, IHC, Flow
Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200
Flow: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: Mouse brain
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 16kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: SNCA Antibody: PD1, NACP, PARK1, PARK4, Alpha-synuclein, Non-A beta component of AD amyloid
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.