SNCA Polyclonal Antibody | E-AB-13070

SNCA Polyclonal Antibody | E-AB-13070 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Alpha synuclein, Alpha-synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, Non-A-beta component of alzheimers disease amyloid, precursor of, Non-A4 component of amyloid precursor, Non-A4 component of amyloid, precursor of, OTTHUMP00000218549, OTTHUMP00000218551, OTTHUMP00000218552, OTTHUMP00000218553, OTTHUMP00000218554, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4, Parkinson disease familial 1, SNCA, Snca synuclein, alpha (non A4 component of amyloid precursor), SYN, Synuclein alpha, Synuclein alpha 140, Synuclein, alpha (non A4 component of amyloid precursor), SYUA

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience

Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

Concentration: 0.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human SNCA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A