LBD
SND1 Antibody (Center) [APR10966G]
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- LBD-APR10966G
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Description
SND1 Antibody (Center) [APR10966G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the Central region of human SND1.
Cellular Localisation: Cytoplasm. Nucleus. Melanosome Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065)
Molecular Weight: 101997
Clone: Polyclonal
Gene Name: SND1
Gene ID: 27044
Function: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:28546213, PubMed:18453631) . As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213) . Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934) . Plays a role in PIM1 regulation of MYB activity (PubMed:9809063) . Functions as a transcriptional coactivator for STAT5 (By similarity) .
Summary: Tissue Location: Ubiquitously expressed.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator, SND1, TDRD11